M2 Macrophage Derived Extracellular Vesicle-Mediated Transfer of MiR-186-5p Promotes Colon Cancer Progression by Targeting DLC1.

Guo, Junfeng; Wang, Xingyu; Guo, Qingdong; Zhu, Shengtao; Li, Peng; Zhang, Shutian; Min, Li

Guo, Junfeng; Wang, Xingyu; Guo, Qingdong; Zhu, Shengtao; Li, Peng; Zhang, Shutian; Min, Li.

Afiliación

Guo J; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.
Wang X; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.
Guo Q; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.
Zhu S; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.
Li P; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.
Zhang S; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.
Min L; Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Disease, Beijing Digestive Disease Center, Beijing Key Laboratory for Precancerous Lesion of Digestive Disease, Beijing, 100050, P. R. China.

Int J Biol Sci ; 18(4): 1663-1676, 2022.

Article en En | MEDLINE | ID: mdl-35280693

Asunto(s)

Neoplasias del Colon; Vesículas Extracelulares; MicroARNs; Neoplasias del Colon/metabolismo; Vesículas Extracelulares/genética; Vesículas Extracelulares/metabolismo; Proteínas Activadoras de GTPasa/genética; Proteínas Activadoras de GTPasa/metabolismo; Humanos; Macrófagos/metabolismo; MicroARNs/genética; MicroARNs/metabolismo; Microambiente Tumoral/genética; Proteínas Supresoras de Tumor/genética; Proteínas Supresoras de Tumor/metabolismo

Palabras clave

Colon cancer (CC); DLC1; Extracellular vesicles (EVs); M2 macrophage; miR-186-5p

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias del Colon / MicroARNs / Vesículas Extracelulares Límite: Humans Idioma: En Revista: Int J Biol Sci Asunto de la revista: BIOLOGIA Año: 2022 Tipo del documento: Article Pais de publicación: Australia

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