Camsap1, calmodulin-regulated spectrin-associated protein 1; Cdc25a, cell division cycle 25A; Cdk8, cyclin dependent kinase 8; Colchicine; Cpt2, carnitine palmitoyl transferase 2; Dmxl1, Dmx Like 1; Dstyk, dual serine/threonine and tyrosine protein kinase; Duoxa2, dual oxidase maturation factor 2; ECM, extracellular matrix; Eml4, EMAP like 4; GO, gene ontology; Gucy2c, guanylate cyclase 2C; Hepatocytes; Hypoosmolarity; Liver perfusion; Liver regeneration; Luc7l3, LUC7 like 3 pre-MRNA splicing factor; Msantd2, Myb/SANT DNA binding domain containing 2; Nags, N-acetyl glutamate synthase; Nfat5, nuclear factor of activated t cells 5; Osmosis; PHx; PHx, partial hepatectomy; PI, propidium iodide; Prmt1, protein arginine methyltransferase 1; RT, room temperature; Rab30, member RAS Oncogene Family; Rps6, ribosomal Protein S6; Scnn1a, sodium channel epithelial 1 subunit alpha; Slc39a10, solute carrier family 39 member 10; Tfeb, transcription factor EB; Timp1, tissue inhibitor of metalloproteinase 1; Zmpste24, zinc metallopeptidase STE24; miR-141-3p; miRNA, microRNA; microRNA; qPCR, quantitative PCR