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Cemiplimab in cutaneous squamous cell carcinomas (SCC): an overview and a clinical case.
Ghidini, Antonio; Santangelo, Domenico; Vaccaro, Giovanni; Chillura, Mario; Petrelli, Fausto.
Afiliación
  • Ghidini A; Oncology Unit, Ospedale Giovanni Paolo II, Sciacca, AG, Italy. Electronic address: antonioghidini@hotmail.com.
  • Santangelo D; ORL Unit, Ospedale Giovanni Paolo II, Sciacca, AG, Italy.
  • Vaccaro G; ORL Unit, Ospedale Giovanni Paolo II, Sciacca, AG, Italy.
  • Chillura M; Oncology Unit, Medical Sciences Department, ASST Bergamo Ovest, Treviglio, BG, Italy.
  • Petrelli F; Oncology Unit, Casa di Cura Igea, Milan, Italy.
Oral Oncol ; 128: 105847, 2022 05.
Article en En | MEDLINE | ID: mdl-35367788
ABSTRACT

INTRODUCTION:

Cemiplimab, a monoclonal antibody directed against the PD-1 receptor of immune cells, has recent indication for the treatment of patients with locally advanced or metastatic cutaneous squamous cell carcinoma (cSCC). CASE DESCRIPTION We present the clinical case of an elderly woman affected by locally advanced squamous carcinoma of the left cheek, in excellent response after only one course of therapy with cemiplimab, with good tolerability.

CONCLUSIONS:

Immunotherapy is a new therapeutic option in cSCC.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Carcinoma de Células Escamosas Límite: Aged / Female / Humans Idioma: En Revista: Oral Oncol Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Carcinoma de Células Escamosas Límite: Aged / Female / Humans Idioma: En Revista: Oral Oncol Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article