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Examining the sustainability of effects of early childhood obesity prevention interventions: Follow-up of the EPOCH individual participant data prospective meta-analysis.
Seidler, Anna Lene; Hunter, Kylie E; Baur, Louise; Espinoza, David; Taylor, Rachael W; Wen, Li Ming; Hesketh, Kylie D; Campbell, Karen; Daniels, Lynne; Mihrshahi, Seema; Rissel, Chris; Taylor, Barry; Askie, Lisa M.
Afiliación
  • Seidler AL; NHMRC Clinical Trials Centre, University of Sydney, Camperdown, New South Wales, Australia.
  • Hunter KE; NHMRC Clinical Trials Centre, University of Sydney, Camperdown, New South Wales, Australia.
  • Baur L; Specialty of Child and Adolescent Health, University of Sydney, Camperdown, New South Wales, Australia.
  • Espinoza D; NHMRC Clinical Trials Centre, University of Sydney, Camperdown, New South Wales, Australia.
  • Taylor RW; Department of Medicine, University of Otago, Dunedin, New Zealand.
  • Wen LM; Health Promotion Unit, Sydney Local Health District, School of Public Health, University of Sydney, Camperdown, New South Wales, Australia.
  • Hesketh KD; Institute for Physical Activity and Nutrition, Deakin University, Geelong, Victoria, Australia.
  • Campbell K; Institute for Physical Activity and Nutrition, Deakin University, Geelong, Victoria, Australia.
  • Daniels L; Centre Child Health Research, School Exercise Nutrition Sciences, Queensland University Technology, Brisbane, Queensland, Australia.
  • Mihrshahi S; Department of Health Systems and Populations, Faculty of Medicine, Health and Human Sciences, Macquarie University, New South Wales, Australia.
  • Rissel C; Sydney School of Public Health, University of Sydney, Camperdown, New South Wales, Australia.
  • Taylor B; Department of Women's and Children's Health, University of Otago, Dunedin, New Zealand.
  • Askie LM; NHMRC Clinical Trials Centre, University of Sydney, Camperdown, New South Wales, Australia.
Pediatr Obes ; 17(9): e12919, 2022 09.
Article en En | MEDLINE | ID: mdl-35396815
ABSTRACT

BACKGROUND:

Although early childhood obesity prevention has become an important issue internationally, little evidence exists regarding longer term effects (i.e., sustainability) of early interventions.

OBJECTIVE:

To determine whether intervention benefits at 2 years of age were sustained at 3.5 and 5 years.

METHODS:

Follow-up of the Early Prevention of Obesity in Children (EPOCH) individual participant data prospective meta-analysis of four randomized controlled trials including 2196 mother-child dyads at baseline. Interventions were home- or community-based, commenced within 6 months of birth, ended by 2 years of age, and comprised multiple sessions. Controls received standard care. BMI z-score (primary outcome), other anthropometric measures and weight-related behaviours were initially measured at 1.5-2 years and followed up at 3.5 and 5 years.

RESULTS:

Positive intervention effects on BMI z-scores at 1.5-2 years of age were not apparent by 3.5 years (-0.04 adjusted mean difference; 95% CI-0.14, 0.06; p = 0.424), and 5 years (0.03; 95% CI -0.08, 0.14; p = 0.60). While prolonged intervention benefits were detected for a few, but not the majority of, weight-related behaviours at 3.5 years, these effects diminished over time.

CONCLUSION:

This meta-analysis found that initial positive effects of childhood obesity interventions faded out after interventions ended, pointing toward the importance of a suite of interventions implemented at multiple stages across childhood.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obesidad Infantil Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies / Systematic_reviews Límite: Child / Child, preschool / Humans Idioma: En Revista: Pediatr Obes Año: 2022 Tipo del documento: Article País de afiliación: Australia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obesidad Infantil Tipo de estudio: Clinical_trials / Observational_studies / Prognostic_studies / Systematic_reviews Límite: Child / Child, preschool / Humans Idioma: En Revista: Pediatr Obes Año: 2022 Tipo del documento: Article País de afiliación: Australia