Examining the sustainability of effects of early childhood obesity prevention interventions: Follow-up of the EPOCH individual participant data prospective meta-analysis.
Pediatr Obes
; 17(9): e12919, 2022 09.
Article
en En
| MEDLINE
| ID: mdl-35396815
ABSTRACT
BACKGROUND:
Although early childhood obesity prevention has become an important issue internationally, little evidence exists regarding longer term effects (i.e., sustainability) of early interventions.OBJECTIVE:
To determine whether intervention benefits at 2 years of age were sustained at 3.5 and 5 years.METHODS:
Follow-up of the Early Prevention of Obesity in Children (EPOCH) individual participant data prospective meta-analysis of four randomized controlled trials including 2196 mother-child dyads at baseline. Interventions were home- or community-based, commenced within 6 months of birth, ended by 2 years of age, and comprised multiple sessions. Controls received standard care. BMI z-score (primary outcome), other anthropometric measures and weight-related behaviours were initially measured at 1.5-2 years and followed up at 3.5 and 5 years.RESULTS:
Positive intervention effects on BMI z-scores at 1.5-2 years of age were not apparent by 3.5 years (-0.04 adjusted mean difference; 95% CI-0.14, 0.06; p = 0.424), and 5 years (0.03; 95% CI -0.08, 0.14; p = 0.60). While prolonged intervention benefits were detected for a few, but not the majority of, weight-related behaviours at 3.5 years, these effects diminished over time.CONCLUSION:
This meta-analysis found that initial positive effects of childhood obesity interventions faded out after interventions ended, pointing toward the importance of a suite of interventions implemented at multiple stages across childhood.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Obesidad Infantil
Tipo de estudio:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
/
Systematic_reviews
Límite:
Child
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Child, preschool
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Humans
Idioma:
En
Revista:
Pediatr Obes
Año:
2022
Tipo del documento:
Article
País de afiliación:
Australia