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A highly stable human single-domain antibody-drug conjugate exhibits superior penetration and treatment of solid tumors.
Wu, Yanling; Li, Quanxiao; Kong, Yu; Wang, Zhi; Lei, Cheng; Li, Ji; Ding, Lulu; Wang, Chunyu; Cheng, Yaping; Wei, Yaozhu; Song, Yuanlin; Yang, Zhenlin; Tu, Chao; Ding, Yu; Ying, Tianlei.
Afiliación
  • Wu Y; MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China; Shanghai Engineering Research Center for Synthetic Immunology, Shanghai 200032, China. Electronic address:
  • Li Q; MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
  • Kong Y; MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
  • Wang Z; MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
  • Lei C; Biomissile Corporation, Shanghai 201203, China.
  • Li J; Department of Pancreatic Surgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Ding L; State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China.
  • Wang C; MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
  • Cheng Y; MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
  • Wei Y; Mabplex International, Yantai, Shandong 264006, China.
  • Song Y; Shanghai Key Laboratory of Lung Inflammation and Injury, Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
  • Yang Z; Shanghai Engineering Research Center for Synthetic Immunology, Shanghai 200032, China; Shanghai Key Laboratory of Lung Inflammation and Injury, Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
  • Tu C; Shanghai Engineering Research Center for Synthetic Immunology, Shanghai 200032, China; Biomissile Corporation, Shanghai 201203, China.
  • Ding Y; State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai 200438, China. Electronic address: yuding@fudan.edu.cn.
  • Ying T; MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China; Shanghai Engineering Research Center for Synthetic Immunology, Shanghai 200032, China. Electronic address:
Mol Ther ; 30(8): 2785-2799, 2022 08 03.
Article en En | MEDLINE | ID: mdl-35462042
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoconjugados / Anticuerpos de Dominio Único / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoconjugados / Anticuerpos de Dominio Único / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos