How fluorescent labels affect the kinetics of the toehold-mediated DNA strand displacement reaction.
Chem Commun (Camb)
; 58(39): 5849-5852, 2022 May 12.
Article
en En
| MEDLINE
| ID: mdl-35467686
End modification of the toehold domain or near to it using fluorophore dyes or quenchers can significantly modulate the kinetics of the toehold-mediated strand displacement reaction (TMSDR) by almost two orders of magnitude. The labels at the end of the signal strand impede the TMSDR, while those at the end of the toehold domain of the substrate strand accelerate the TMSDR kinetics.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
ADN
/
Colorantes Fluorescentes
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2022
Tipo del documento:
Article
Pais de publicación:
Reino Unido