Aerobic copper-promoted oxidative dehydrosulfurative carbon-oxygen cross-coupling of 3,4-dihydropyrimidine-1H-2-thiones with alcohols.
RSC Adv
; 11(58): 36821-36825, 2021 Nov 10.
Article
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| MEDLINE
| ID: mdl-35494373
ABSTRACT
An aerobic Cu-promoted oxidative dehydrosulfurative carbon-oxygen cross-coupling of 3,4-dihydropyrimidin-1H-2-thiones (DHPMs) with both aliphatic and aromatic alcohols is described. Together with the ready availability of DHPMs and both alcohols, the method furnishes facile access to biologically valuable 2-alkoxypyrimidines with rapid diversification.
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01-internacional
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MEDLINE
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En
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RSC Adv
Año:
2021
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Article