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An open-label, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single doses of GSK2586881 in participants with pulmonary arterial hypertension.
Simon, Marc A; Hanrott, Kate; Budd, David C; Torres, Fernando; Grünig, Ekkehard; Escribano-Subias, Pilar; Meseguer, Manuel L; Halank, Michael; Opitz, Christian; Hall, David A; Hewens, Deborah; Powley, William M; Siederer, Sarah; Bayliffe, Andrew; Lazaar, Aili L; Cahn, Anthony; Rosenkranz, Stephan.
Afiliación
  • Simon MA; Division of Cardiology, Department of Medicine University of California San Francisco California USA.
  • Hanrott K; Research and Development, Medicines Research Centre GlaxoSmithKline plc. Stevenage UK.
  • Budd DC; Research and Development, Medicines Research Centre GlaxoSmithKline plc. Stevenage UK.
  • Torres F; UT Southwestern Medical Center Dallas Texas USA.
  • Grünig E; Centre for Pulmonary Hypertension Thoraxklinik Heidelberg gGmbH at Heidelberg University Hospital Heidelberg Germany.
  • Escribano-Subias P; CIBER-CV Cardiology Department, Pulmonary Hypertension Unit Hospital Universitario 12 de Octubre Madrid Spain.
  • Meseguer ML; Lung Transplant and Pulmonary Vascular Diseases Department Hospital Universitari Vall d'Hebron Barcelona Spain.
  • Halank M; Department of Internal Medicine I University Hospital Carl Gustav Carus Dresden Germany.
  • Opitz C; Department of Cardiology DRK Kliniken Berlin Germany.
  • Hall DA; Department of Cardiology, University Heart Center Berlin Charité University Medicine Berlin Germany.
  • Hewens D; Research and Development, Medicines Research Centre GlaxoSmithKline plc. Stevenage UK.
  • Powley WM; Research and Development, Medicines Research Centre GlaxoSmithKline plc. Stevenage UK.
  • Siederer S; Research and Development, Medicines Research Centre GlaxoSmithKline plc. Stevenage UK.
  • Bayliffe A; Research and Development, Medicines Research Centre GlaxoSmithKline plc. Stevenage UK.
  • Lazaar AL; Research and Development, Medicines Research Centre GlaxoSmithKline plc. Stevenage UK.
  • Cahn A; Marengo Therapeutics and Apple Tree Partners Cambridge Massachusetts USA.
  • Rosenkranz S; Discovery Medicine, Clinical Pharmacology and Experimental Medicine GlaxoSmithKline plc. Collegeville Pennsylvania USA.
Pulm Circ ; 12(1): e12024, 2022 Jan.
Article en En | MEDLINE | ID: mdl-35506108
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials Idioma: En Revista: Pulm Circ Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials Idioma: En Revista: Pulm Circ Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos