Continuous flow mechanochemistry: reactive extrusion as an enabling technology in organic synthesis.
Chem Soc Rev
; 51(11): 4243-4260, 2022 Jun 06.
Article
en En
| MEDLINE
| ID: mdl-35506866
ABSTRACT
Rapid and wide-ranging developments have established mechanochemistry as a powerful avenue in sustainable organic synthesis. This is primarily due to unique opportunities which have been offered in solvent-free - or highly solvent-minimised - reaction systems. Nevertheless, despite elegant advances in ball-milling technology, limitations in scale-up still remain. This tutorial review covers the first reports into the translation from "batch-mode" ball-milling to "flow-mode" reactive extrusion, using twin-screw extrusion.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Técnicas de Química Sintética
Idioma:
En
Revista:
Chem Soc Rev
Año:
2022
Tipo del documento:
Article
País de afiliación:
Reino Unido