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Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery.
Dileep, K V; Ihara, Kentaro; Mishima-Tsumagari, Chiemi; Kukimoto-Niino, Mutsuko; Yonemochi, Mayumi; Hanada, Kazuharu; Shirouzu, Mikako; Zhang, Kam Y J.
Afiliación
  • Dileep KV; Laboratory for Structural Bioinformatics, Center for Biosystems Dynamics Research, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, Kanagawa 230-0045, Japan; Laboratory for Computational and Structural Biology, Jubilee Centre for Medical Research, Jubilee Mission Medical College and Research Institute, Thr
  • Ihara K; Laboratory for Protein Functional and Structural Biology, Center for Biosystems Dynamics Research, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, Kanagawa 230-0045, Japan; Drug Discovery Structural Biology Platform Unit, Center for Biosystems Dynamics Research, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, K
  • Mishima-Tsumagari C; Laboratory for Protein Functional and Structural Biology, Center for Biosystems Dynamics Research, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.
  • Kukimoto-Niino M; Laboratory for Protein Functional and Structural Biology, Center for Biosystems Dynamics Research, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, Kanagawa 230-0045, Japan; Drug Discovery Structural Biology Platform Unit, Center for Biosystems Dynamics Research, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, K
  • Yonemochi M; Drug Discovery Structural Biology Platform Unit, Center for Biosystems Dynamics Research, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.
  • Hanada K; Laboratory for Protein Functional and Structural Biology, Center for Biosystems Dynamics Research, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, Kanagawa 230-0045, Japan; Drug Discovery Structural Biology Platform Unit, Center for Biosystems Dynamics Research, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, K
  • Shirouzu M; Laboratory for Protein Functional and Structural Biology, Center for Biosystems Dynamics Research, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, Kanagawa 230-0045, Japan; Drug Discovery Structural Biology Platform Unit, Center for Biosystems Dynamics Research, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, K
  • Zhang KYJ; Laboratory for Structural Bioinformatics, Center for Biosystems Dynamics Research, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, Kanagawa 230-0045, Japan. Electronic address: kamzhang@riken.jp.
Int J Biol Macromol ; 210: 172-181, 2022 Jun 15.
Article en En | MEDLINE | ID: mdl-35526766
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tacrina / Enfermedad de Alzheimer Límite: Aged / Humans Idioma: En Revista: Int J Biol Macromol Año: 2022 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tacrina / Enfermedad de Alzheimer Límite: Aged / Humans Idioma: En Revista: Int J Biol Macromol Año: 2022 Tipo del documento: Article Pais de publicación: Países Bajos