SARS-CoV-2 variants - Evolution, spike protein, and vaccines.
Biomed J
; 45(4): 573-579, 2022 08.
Article
en En
| MEDLINE
| ID: mdl-35526825
ABSTRACT
Despite the rising natural and vaccines mediated immunity, several countries have experienced a resurgence of the Coronavirus disease of 2019 (COVID-19) due to the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. From Alpha to Omicron, the variants of concern (VOC) have evolved several spike protein mutations that may have an impact on virus characteristics, such as transmissibility and antigenicity. In this review, we describe the evolution of SARS-CoV-2, summarize current knowledge of epidemiological and clinical features of the variants, and discuss the response strategies in terms of vaccines to reduce the burden of COVID-19.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Glicoproteína de la Espiga del Coronavirus
/
Vacunas contra la COVID-19
/
COVID-19
Límite:
Humans
Idioma:
En
Revista:
Biomed J
Año:
2022
Tipo del documento:
Article
País de afiliación:
Taiwán