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Preclinical validation and phase I trial of 4-hydroxysalicylanilide, targeting ribonucleotide reductase mediated dNTP synthesis in multiple myeloma.
Xie, Yongsheng; Wang, Yingcong; Xu, Zhijian; Lu, Yumeng; Song, Dongliang; Gao, Lu; Yu, Dandan; Li, Bo; Chen, Gege; Zhang, Hui; Feng, Qilin; Zhang, Yong; Hu, Ke; Huang, Cheng; Peng, Yu; Wu, Xiaosong; Mao, Zhiyong; Shao, Jimin; Zhu, Weiliang; Shi, Jumei.
Afiliación
  • Xie Y; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 YanChang Road, Shanghai, 200072, China.
  • Wang Y; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 YanChang Road, Shanghai, 200072, China.
  • Xu Z; CAS Key Laboratory of Receptor Research; State Key Laboratory of Drug Research; Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China.
  • Lu Y; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 YanChang Road, Shanghai, 200072, China.
  • Song D; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 YanChang Road, Shanghai, 200072, China.
  • Gao L; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 YanChang Road, Shanghai, 200072, China.
  • Yu D; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 YanChang Road, Shanghai, 200072, China.
  • Li B; CAS Key Laboratory of Receptor Research; State Key Laboratory of Drug Research; Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China.
  • Chen G; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 YanChang Road, Shanghai, 200072, China.
  • Zhang H; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 YanChang Road, Shanghai, 200072, China.
  • Feng Q; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 YanChang Road, Shanghai, 200072, China.
  • Zhang Y; CAS Key Laboratory of Receptor Research; State Key Laboratory of Drug Research; Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China.
  • Hu K; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 YanChang Road, Shanghai, 200072, China.
  • Huang C; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 YanChang Road, Shanghai, 200072, China.
  • Peng Y; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 YanChang Road, Shanghai, 200072, China.
  • Wu X; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 YanChang Road, Shanghai, 200072, China.
  • Mao Z; Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.
  • Shao J; Department of Pathology and Pathophysiology, Cancer Institute of the Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University Cancer Center, 866 Yuhangtang Road, Hangzhou, 310058, Zhejiang, China. shaojimin@zju.edu.cn.
  • Zhu W; CAS Key Laboratory of Receptor Research; State Key Laboratory of Drug Research; Drug Discovery and Design Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai, 201203, China. wlzhu@simm.ac.cn.
  • Shi J; Department of Hematology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, 301 YanChang Road, Shanghai, 200072, China. shijumei@tongji.edu.cn.
J Biomed Sci ; 29(1): 32, 2022 May 12.
Article en En | MEDLINE | ID: mdl-35546402
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ribonucleótido Reductasas / Mieloma Múltiple Límite: Humans Idioma: En Revista: J Biomed Sci Asunto de la revista: MEDICINA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ribonucleótido Reductasas / Mieloma Múltiple Límite: Humans Idioma: En Revista: J Biomed Sci Asunto de la revista: MEDICINA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido