Protective mechanisms of 10-gingerol against myocardial ischemia may involve activation of JAK2/STAT3 pathway and regulation of Ca<sup>2+</sup> homeostasis.

Han, Xue; Qi, Jiaying; Yang, Yakun; Zheng, Bin; Liu, Miaomiao; Liu, Yu; Li, Li; Guan, Shengjiang; Jia, Qingzhong; Chu, Li

Protective mechanisms of 10-gingerol against myocardial ischemia may involve activation of JAK2/STAT3 pathway and regulation of Ca²⁺ homeostasis.

Han, Xue; Qi, Jiaying; Yang, Yakun; Zheng, Bin; Liu, Miaomiao; Liu, Yu; Li, Li; Guan, Shengjiang; Jia, Qingzhong; Chu, Li.

Afiliación

Han X; School of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, China.
Qi J; School of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, China.
Yang Y; School of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, China.
Zheng B; School of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, China.
Liu M; School of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, China.
Liu Y; School of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, China.
Li L; School of Pharmacy, Hebei Medical University, Shijiazhuang, Hebei 050200, China.
Guan S; Affiliated Hospital, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050011, China; School of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, China. Electronic address: guanshengjiang123@126.com.
Jia Q; School of Pharmacy, Hebei Medical University, Shijiazhuang, Hebei 050200, China. Electronic address: qizhjia@hebmu.edu.cn.
Chu L; School of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, China; Hebei Key Laboratory of Chinese Medicine Research on Cardio-cerebrovascular Disease, Shijiazhuang, Hebei 050200, China. Electronic address: chuli0614@126.com.

Biomed Pharmacother ; 151: 113082, 2022 Jul.

Article en En | MEDLINE | ID: mdl-35569350

Asunto(s)

Enfermedad de la Arteria Coronaria; Isquemia Miocárdica; Animales; Apoptosis; Catecoles; Enfermedad de la Arteria Coronaria/patología; Alcoholes Grasos; Homeostasis; Janus Quinasa 2/metabolismo; Isquemia Miocárdica/metabolismo; Miocitos Cardíacos; Ratas; Ratas Sprague-Dawley; Factor de Transcripción STAT3/metabolismo

Palabras clave

10-Gingerol; Ca(2+) transient; JAK2/STAT3 pathway; L-type Ca(2+) channels; Myocardial ischemia

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Isquemia Miocárdica Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Biomed Pharmacother Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Francia

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