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Overall equipment effectiveness, efficiency and slide review analysis of high-end hematology analyzers.
Rastogi, Shubham; Chandran Nair, Sukesh; Murugan, Pandiyan; Sukumar, Asady Sukanya; Mammen, Joy J; Mullai, Saravanan.
Afiliación
  • Rastogi S; HORIBA Medical, HORIBA ABX SAS, Parc Euromédecine - Rue du Caducée, France.
  • Chandran Nair S; Department of Transfusion Medicine & Immunohematology, Christian Medical College, Vellore, Tamil Nadu, India.
  • Murugan P; Department of Transfusion Medicine & Immunohematology, Christian Medical College, Vellore, Tamil Nadu, India.
  • Sukumar AS; Department of Transfusion Medicine & Immunohematology, Christian Medical College, Vellore, Tamil Nadu, India.
  • Mammen JJ; Department of Transfusion Medicine & Immunohematology, Christian Medical College, Vellore, Tamil Nadu, India.
  • Mullai S; Department of Transfusion Medicine & Immunohematology, Christian Medical College, Vellore, Tamil Nadu, India.
Pract Lab Med ; 30: e00275, 2022 May.
Article en En | MEDLINE | ID: mdl-35601458
This study evaluated and compared the overall equipment effectiveness (OEE), sensitivity, specificity, and efficiency of the high-end hematology analyzers, Yumizen H2500, DxH 800, DxH 900 and XN-9000 (XN-10). A total of 400 anonymized left over's K2 EDTA whole blood samples were analyzed for complete blood count. Of 400 samples, 200 were tested on Yumizen H2500; DxH 800 & DxH 900 while the other 200 were tested on Yumizen H2500 & XN-9000 (XN-10), respectively. The OEE was good and comparable for all the hematology analyzers except DxH 800 showing an average status. The sensitivity (%), specificity (%) and turnaround time (in minutes) for Yumizen H2500, DxH 800, DxH 900 and XN-9000 (XN-10) were 91.67, 61.11 & 103; 66.67, 54.55, & 149; 83.33, 27.27 & 136; 83.33, 28.57 & 122, respectively. Confusion matrix highlights the difficulty for DxH 800 and DxH 900 to discriminate left shift or blasts with large hyper-segmented neutrophils. The flags triggered by Yumizen H2500 were markedly changed to large hyper-segmented neutrophils. Lymphoblast caused more confusion for XN-9000 (XN-10), as it came out to be atypical lymphocytes, or hypersegmented neutrophils. Although comparable in OEE index to other analyzers, the Yumizen H2500 seems to be more reliable in detecting the abnormal cells as it has high sensitivity, specificity and less turnaround time. Thus, analysis adding specificity, sensitivity, and efficiency parameters to the OEE index provides more reliable information of the analyzers.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pract Lab Med Año: 2022 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pract Lab Med Año: 2022 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Países Bajos