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Intra-arterial chemoradiotherapy for locally advanced buccal mucosal cancer in an elderly patient with multiple comorbidities: A case report.
Taniguchi, Akito; Toyomasu, Yutaka; Takada, Akinori; Mase, Takamitsu; Kurohara, Kazuto; Omori, Kazuki; Nanpei, Yui; Kawamura, Tomoko; Sakuma, Hajime; Nomoto, Yoshihito.
Afiliación
  • Taniguchi A; Department of Radiology, Mie University Hospital, Tsu, Mie, Japan.
  • Toyomasu Y; Department of Radiology, Mie University Hospital, Tsu, Mie, Japan.
  • Takada A; Department of Radiology, Mie University Hospital, Tsu, Mie, Japan.
  • Mase T; Department of Radiology, Mie University Hospital, Tsu, Mie, Japan.
  • Kurohara K; Department of Oral and Maxillofacial Surgery, Mie University Hospital, Tsu, Mie, Japan.
  • Omori K; Department of Radiology, Mie University Hospital, Tsu, Mie, Japan.
  • Nanpei Y; Department of Radiology, Mie University Hospital, Tsu, Mie, Japan.
  • Kawamura T; Department of Radiology, Mie University Hospital, Tsu, Mie, Japan.
  • Sakuma H; Department of Radiology, Mie University Hospital, Tsu, Mie, Japan.
  • Nomoto Y; Department of Radiology, Mie University Hospital, Tsu, Mie, Japan.
Cancer Rep (Hoboken) ; 5(9): e1629, 2022 09.
Article en En | MEDLINE | ID: mdl-35611846
ABSTRACT

BACKGROUND:

The management of locally advanced oral cavity squamous cell carcinoma (LA-OCScc) in elderly patients with multiple comorbidities is difficult. CASE We report the case of an elderly patient with buccal mucosal squamous cell carcinoma as well as chronic renal dysfunction, hepatic cirrhosis, rheumatoid arthritis, and metachronous diffuse large B-cell lymphoma. We performed radiation therapy (a total dose of 70 Gy in 35 fractions) and six cycles of intra-arterial chemotherapy with 40 mg/m2 cisplatin per week. After treatment, the tumor completely disappeared, and there was no recurrence or deterioration of comorbidities during the 12-month follow-up period.

CONCLUSION:

Intra-arterial chemoradiotherapy may be a good treatment option for LA-OCScc in elderly patients with multiple comorbidities.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Boca / Carcinoma de Células Escamosas Tipo de estudio: Observational_studies / Prognostic_studies Límite: Aged / Humans Idioma: En Revista: Cancer Rep (Hoboken) Año: 2022 Tipo del documento: Article País de afiliación: Japón

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Boca / Carcinoma de Células Escamosas Tipo de estudio: Observational_studies / Prognostic_studies Límite: Aged / Humans Idioma: En Revista: Cancer Rep (Hoboken) Año: 2022 Tipo del documento: Article País de afiliación: Japón