Emerging mechanisms of targeted protein degradation by molecular glues.

Frere, Geordon A; de Araujo, Elvin D; Gunning, Patrick T

Frere, Geordon A; de Araujo, Elvin D; Gunning, Patrick T.

Afiliación

Frere GA; Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, ON, Canada; Department of Chemistry, University of Toronto, Toronto, ON, Canada. Electronic address: geordi.frere@mail.utoronto.ca.
de Araujo ED; Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, ON, Canada.
Gunning PT; Department of Chemical and Physical Sciences, University of Toronto Mississauga, Mississauga, ON, Canada; Department of Chemistry, University of Toronto, Toronto, ON, Canada. Electronic address: patrick.gunning@utoronto.ca.

Methods Cell Biol ; 169: 1-26, 2022.

Article en En | MEDLINE | ID: mdl-35623698

Asunto(s)

Proteoma; Ubiquitina-Proteína Ligasas; Humanos; Ligandos; Unión Proteica; Proteolisis; Proteoma/metabolismo; Ubiquitina-Proteína Ligasas/metabolismo

Palabras clave

Chemically induced proximity; E3 ligase; Molecular glues; Monovalent; Protein degraders; Targeted protein degradation; Ubiquitin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteoma / Ubiquitina-Proteína Ligasas Límite: Humans Idioma: En Revista: Methods Cell Biol Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos

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