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Perinatal Obesity Induces Hepatic Growth Restriction with Increased DNA Damage Response, Senescence, and Dysregulated Igf-1-Akt-Foxo1 Signaling in Male Offspring of Obese Mice.
Kasper, Philipp; Selle, Jaco; Vohlen, Christina; Wilke, Rebecca; Kuiper-Makris, Celien; Klymenko, Oleksiy; Bae-Gartz, Inga; Schömig, Charlotte; Quaas, Alexander; Schumacher, Björn; Demir, Münevver; Bürger, Martin; Lang, Sonja; Martin, Anna; Steffen, Hans-Michael; Goeser, Tobias; Dötsch, Jörg; Alcazar, Miguel A Alejandre.
Afiliación
  • Kasper P; Clinic for Gastroenterology and Hepatology, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
  • Selle J; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics-Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
  • Vohlen C; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics-Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
  • Wilke R; Department of Pediatric and Adolescent Medicine, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
  • Kuiper-Makris C; The German Centre for Lung Research (DZL), Marburg Lung Centre (UGMLC), Institute for Lung Health, Justus-Liebig University Giessen, 35392 Giessen, Germany.
  • Klymenko O; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics-Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
  • Bae-Gartz I; Department of Pediatric and Adolescent Medicine, Translational Experimental Pediatrics-Experimental Pulmonology, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
  • Schömig C; Department of Pediatric and Adolescent Medicine, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
  • Quaas A; The German Centre for Lung Research (DZL), Marburg Lung Centre (UGMLC), Institute for Lung Health, Justus-Liebig University Giessen, 35392 Giessen, Germany.
  • Schumacher B; Department of Pediatric and Adolescent Medicine, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
  • Demir M; Department of Pediatric and Adolescent Medicine, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
  • Bürger M; Department of Pathology, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
  • Lang S; Cologne Excellence Cluster for Stress Responses in Ageing-Associated Diseases (CECAD), University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
  • Martin A; University Hospital Cologne, Faculty of Medicine, Institute for Genome Stability in Aging and Disease, University of Cologne, 50937 Cologne, Germany.
  • Steffen HM; Department of Hepatology and Gastroenterology, Campus Virchow Clinic, Charité Campus Mitte, Charité University Medicine Berlin, 10117 Berlin, Germany.
  • Goeser T; Clinic for Gastroenterology and Hepatology, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
  • Dötsch J; Clinic for Gastroenterology and Hepatology, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
  • Alcazar MAA; Clinic for Gastroenterology and Hepatology, University Hospital Cologne, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
Int J Mol Sci ; 23(10)2022 May 17.
Article en En | MEDLINE | ID: mdl-35628414
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Efectos Tardíos de la Exposición Prenatal / Factor I del Crecimiento Similar a la Insulina / Proteínas Proto-Oncogénicas c-akt / Proteína Forkhead Box O1 / Obesidad Materna Tipo de estudio: Etiology_studies Límite: Animals / Pregnancy Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Efectos Tardíos de la Exposición Prenatal / Factor I del Crecimiento Similar a la Insulina / Proteínas Proto-Oncogénicas c-akt / Proteína Forkhead Box O1 / Obesidad Materna Tipo de estudio: Etiology_studies Límite: Animals / Pregnancy Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Suiza