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HER2 G776S mutation promotes oncogenic potential in colorectal cancer cells when accompanied by loss of APC function.
Mitani, Yosuke; Ohashi, Shinya; Kikuchi, Osamu; Nakai, Yukie; Ida, Tomomi; Mizumoto, Ayaka; Yamamoto, Yoshihiro; Saito, Tomoki; Kataoka, Shigeki; Matsubara, Junichi; Yamada, Atsushi; Kanai, Masashi; Matsumoto, Shigemi; Sakai, Hiroaki; Yoshikawa, Kiyotsugu; Nakamura, Eijiro; Muto, Manabu.
Afiliación
  • Mitani Y; Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Ohashi S; Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Kikuchi O; Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Nakai Y; Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Ida T; Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Mizumoto A; Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Yamamoto Y; Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Saito T; Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Kataoka S; Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Matsubara J; Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Yamada A; Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Kanai M; Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Matsumoto S; Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Sakai H; DSK Project, Medical Innovation Center, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Yoshikawa K; Department of Clinical Pharmacy Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Keisui-kan, 97-1 Minami-hodate Kodo, Kyotanabe, Kyoto, W604610-0395, Japan.
  • Nakamura E; Department of Urology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
  • Muto M; Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. mmuto@kuhp.kyoto-u.ac.jp.
Sci Rep ; 12(1): 9213, 2022 06 02.
Article en En | MEDLINE | ID: mdl-35654814
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oncogenes / Neoplasias Colorrectales Límite: Humans Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Oncogenes / Neoplasias Colorrectales Límite: Humans Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido