Chlorogenic acid exerts neuroprotective effect against hypoxia-ischemia brain injury in neonatal rats by activating Sirt1 to regulate the Nrf2-NF-&#954;B signaling pathway.

Zheng, Yihui; Li, Luyao; Chen, Binwen; Fang, Yu; Lin, Wei; Zhang, Tianlei; Feng, Xiaoli; Tao, Xiaoyue; Wu, Yiqing; Fu, Xiaoqin; Lin, Zhenlang

Chlorogenic acid exerts neuroprotective effect against hypoxia-ischemia brain injury in neonatal rats by activating Sirt1 to regulate the Nrf2-NF-κB signaling pathway.

Zheng, Yihui; Li, Luyao; Chen, Binwen; Fang, Yu; Lin, Wei; Zhang, Tianlei; Feng, Xiaoli; Tao, Xiaoyue; Wu, Yiqing; Fu, Xiaoqin; Lin, Zhenlang.

Afiliación

Zheng Y; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Li L; School of Second Clinical Medical, Wenzhou Medical University, Wenzhou, China.
Chen B; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Fang Y; School of Second Clinical Medical, Wenzhou Medical University, Wenzhou, China.
Lin W; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Zhang T; School of Second Clinical Medical, Wenzhou Medical University, Wenzhou, China.
Feng X; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Tao X; School of Second Clinical Medical, Wenzhou Medical University, Wenzhou, China.
Wu Y; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Fu X; School of Second Clinical Medical, Wenzhou Medical University, Wenzhou, China.
Lin Z; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.

Cell Commun Signal ; 20(1): 84, 2022 06 10.

Article en En | MEDLINE | ID: mdl-35689269

Asunto(s)

Lesiones Encefálicas; Hipoxia-Isquemia Encefálica; Fármacos Neuroprotectores; Animales; Animales Recién Nacidos; Encéfalo/metabolismo; Lesiones Encefálicas/tratamiento farmacológico; Lesiones Encefálicas/metabolismo; Lesiones Encefálicas/patología; Ácido Clorogénico/metabolismo; Ácido Clorogénico/farmacología; Ácido Clorogénico/uso terapéutico; Hipoxia-Isquemia Encefálica/complicaciones; Hipoxia-Isquemia Encefálica/tratamiento farmacológico; Hipoxia-Isquemia Encefálica/metabolismo; Infarto/tratamiento farmacológico; Infarto/metabolismo; Infarto/patología; Inflamación/metabolismo; Isquemia/metabolismo; Factor 2 Relacionado con NF-E2/metabolismo; FN-kappa B/metabolismo; Fármacos Neuroprotectores/metabolismo; Fármacos Neuroprotectores/farmacología; Fármacos Neuroprotectores/uso terapéutico; Ratas; Ratas Sprague-Dawley; Transducción de Señal; Sirtuina 1/metabolismo

Palabras clave

Chlorogenic acid; Hie; Nrf2-NF-κB; Sirt1

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lesiones Encefálicas / Fármacos Neuroprotectores / Hipoxia-Isquemia Encefálica Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Cell Commun Signal Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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