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Biofilm accumulation and sucrose rinse modulate calcium and fluoride bioavailability in the saliva of children with early childhood caries.
Crescente, Camila Lopes; de Sousa, Emerson Tavares; Lima-Holanda, Aline Tavares; Steiner-Oliveira, Carolina; Nobre-Dos-Santos, Marinês.
Afiliación
  • Crescente CL; Department of Health Sciences and Pediatric Dentistry, Piracicaba Dental School, University of Campinas-UNICAMP, Limeira Avenue 901, Piracicaba, SP, CEP 13414-903, Brazil.
  • de Sousa ET; Department of Health Sciences and Pediatric Dentistry, Piracicaba Dental School, University of Campinas-UNICAMP, Limeira Avenue 901, Piracicaba, SP, CEP 13414-903, Brazil.
  • Lima-Holanda AT; Department of Health Sciences and Pediatric Dentistry, Piracicaba Dental School, University of Campinas-UNICAMP, Limeira Avenue 901, Piracicaba, SP, CEP 13414-903, Brazil.
  • Steiner-Oliveira C; Department of Health Sciences and Pediatric Dentistry, Piracicaba Dental School, University of Campinas-UNICAMP, Limeira Avenue 901, Piracicaba, SP, CEP 13414-903, Brazil.
  • Nobre-Dos-Santos M; Department of Health Sciences and Pediatric Dentistry, Piracicaba Dental School, University of Campinas-UNICAMP, Limeira Avenue 901, Piracicaba, SP, CEP 13414-903, Brazil. nobre@fop.unicamp.br.
Sci Rep ; 12(1): 10283, 2022 06 18.
Article en En | MEDLINE | ID: mdl-35717506
This study aimed at investigating the combined effect of biofilm accumulation and 20% sucrose rinse on the modulation of calcium (Ca2+), phosphate (Pi), and fluoride (F-) bioavailability in the saliva of children with early childhood caries (ECC). Fifty-six preschoolers of both genders were evaluated according to caries experience and activity: caries-free (CF, n = 28) and with ECC (n = 28) and then, submitted to biofilm intervention (biofilm accumulation). In each situation, saliva samples were collected before and five minutes after a 20% sucrose rinse to determine the concentrations of Ca2+, Pi, and F-. Calcium concentration was significantly lower in the biofilm accumulation situation compared to the situation of biofilm mechanical control (p ≤ 0.01), except for CF children after sucrose rinse. Biofilm accumulation increased salivary calcium concentration in children with ECC after sucrose rinse (p = 0.04), whereas mechanical biofilm control reduced it in both groups (p = 0.000). Phosphate concentration was influenced by mechanical control of biofilm in CF children (p = 0.03). The fluoride bioavailability was reduced by sucrose rinse and biofilm accumulation in CF and ECC children (p ≤ 0.002). In conclusion, the combined effect of biofilm accumulation and sucrose rinse modifies the bioavailability of calcium and fluoride in the saliva of children with early childhood caries.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Caries Dental / Fluoruros Límite: Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Caries Dental / Fluoruros Límite: Child / Child, preschool / Female / Humans / Male Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido