Clinical impact of selumetinib on pediatric elephantiasis neuromatosa.
Pediatr Dermatol
; 39(5): 764-766, 2022 Sep.
Article
en En
| MEDLINE
| ID: mdl-35739628
ABSTRACT
Elephantiasis neuromatosa (EN) is a rare and extreme form of plexiform neurofibroma in patients with neurofibromatosis type 1 (NF1). EN is often associated with significant morbidity and remains difficult to treat. We present a case of an 11-year-old female with NF1 whose thoracolumbar plexiform neurofibroma and lower extremity EN exhibited clinical improvement from treatment with selumetinib, a selective MEK inhibitor.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neurofibromatosis 1
/
Neurofibroma Plexiforme
/
Elefantiasis
Límite:
Child
/
Female
/
Humans
Idioma:
En
Revista:
Pediatr Dermatol
Año:
2022
Tipo del documento:
Article
País de afiliación:
Estados Unidos