RNA editing enzyme ADAR1 controls miR-381-3p-mediated expression of multidrug resistance protein MRP4 via regulation of circRNA in human renal cells.

Omata, Yuji; Okawa, Maseri; Haraguchi, Mai; Tsuruta, Akito; Matsunaga, Naoya; Koyanagi, Satoru; Ohdo, Shigehiro

Omata, Yuji; Okawa, Maseri; Haraguchi, Mai; Tsuruta, Akito; Matsunaga, Naoya; Koyanagi, Satoru; Ohdo, Shigehiro.

Afiliación

Omata Y; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Okawa M; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Haraguchi M; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Tsuruta A; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan; Department of Glocal Healthcare Science, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Matsunaga N; Department of Clinical Pharmacokinetics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Koyanagi S; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan; Department of Glocal Healthcare Science, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan. Electronic address: koyanagi@phar.kyushu-u.ac.jp.
Ohdo S; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan. Electronic address: ohdo@phar.kyushu-u.ac.jp.

J Biol Chem ; 298(8): 102184, 2022 08.

Article en En | MEDLINE | ID: mdl-35753353

Asunto(s)

Adenosina Desaminasa/metabolismo; MicroARNs; Edición de ARN; Proteínas de Unión al ARN/metabolismo; Adenosina/metabolismo; Adenosina Desaminasa/genética; Resistencia a Múltiples Medicamentos; Humanos; Inosina/genética; Riñón/metabolismo; MicroARNs/genética; MicroARNs/metabolismo; Proteínas Asociadas a Resistencia a Múltiples Medicamentos/genética; Proteínas Asociadas a Resistencia a Múltiples Medicamentos/metabolismo; ARN Circular/genética; Proteínas de Unión al ARN/genética

Palabras clave

ABC transporter; RNA editing; RNA splicing; circular RNA; microRNA; posttranscriptional regulation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adenosina Desaminasa / Proteínas de Unión al ARN / Edición de ARN / MicroARNs Límite: Humans Idioma: En Revista: J Biol Chem Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

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