Sesamin protects against neurotoxicity via inhibition of microglial activation under high glucose circumstances through modulating p38 and JNK signaling pathways.

Kongtawelert, Prachya; Kaewmool, Chayanut; Phitak, Thanyaluck; Phimphilai, Mattabhorn; Pothacharoen, Peraphan; Shwe, Thuzar Hla

Kongtawelert, Prachya; Kaewmool, Chayanut; Phitak, Thanyaluck; Phimphilai, Mattabhorn; Pothacharoen, Peraphan; Shwe, Thuzar Hla.

Afiliación

Kongtawelert P; Thailand Excellence Center for Tissue Engineering and Stem Cells, Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand. prachya.k@cmu.ac.th.
Kaewmool C; Thailand Excellence Center for Tissue Engineering and Stem Cells, Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.
Phitak T; Thailand Excellence Center for Tissue Engineering and Stem Cells, Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.
Phimphilai M; Division of Endocrinology, Department of Internal Medicine, Chiang Mai University, Chiang Mai, Thailand.
Pothacharoen P; Thailand Excellence Center for Tissue Engineering and Stem Cells, Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.
Shwe TH; Thailand Excellence Center for Tissue Engineering and Stem Cells, Department of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.

Sci Rep ; 12(1): 11296, 2022 07 04.

Article en En | MEDLINE | ID: mdl-35788665

Asunto(s)

Microglía; Síndromes de Neurotoxicidad; Animales; Medios de Cultivo Condicionados; Dioxoles/farmacología; Glucosa/toxicidad; Lignanos; Sistema de Señalización de MAP Quinasas; Ratones; Ratas

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microglía / Síndromes de Neurotoxicidad Límite: Animals Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article País de afiliación: Tailandia Pais de publicación: Reino Unido

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