Functional and Toxicological Evaluation of MAA-41: A Novel Rationally Designed Antimicrobial Peptide Using Hybridization and Modification Methods from LL-37 and BMAP-28.

Masadeh, Majed; Ayyad, Afnan; Haddad, Razan; Alsaggar, Mohammad; Alzoubi, Karem; Alrabadi, Nasr

Masadeh, Majed; Ayyad, Afnan; Haddad, Razan; Alsaggar, Mohammad; Alzoubi, Karem; Alrabadi, Nasr.

Afiliación

Masadeh M; Department of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan.
Ayyad A; Department of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan.
Haddad R; Department of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan.
Alsaggar M; Department of Pharmaceutical Technology, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan.
Alzoubi K; Department of Pharmacy Practice and Pharmacotherapeutics, University of Sharjah, Sharjah, UAE.
Alrabadi N; Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan.

Curr Pharm Des ; 28(26): 2177-2188, 2022.

Article en En | MEDLINE | ID: mdl-35792128

Asunto(s)

Bacterias Gramnegativas; Bacterias Grampositivas; Animales; Antibacterianos/química; Antibacterianos/farmacología; Péptidos Catiónicos Antimicrobianos/química; Péptidos Catiónicos Antimicrobianos/farmacología; Péptidos Antimicrobianos; Biopelículas; Chlorocebus aethiops; Pruebas de Sensibilidad Microbiana; Proteínas; Células Vero

Palabras clave

Antimicrobial peptides; anti-biofilm activity; antimicrobial resistance; hybridization; multi-drug resistance (MDR); rational design; synergism

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bacterias Gramnegativas / Bacterias Grampositivas Límite: Animals Idioma: En Revista: Curr Pharm Des Asunto de la revista: FARMACIA Año: 2022 Tipo del documento: Article País de afiliación: Jordania Pais de publicación: Emiratos Árabes Unidos

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