Feedback loop between hepatocyte nuclear factor 1&#945; and endoplasmic reticulum stress mitigates liver injury by downregulating hepatocyte apoptosis.

Liu, Si-Ying; Rao, Jian-Xu; Deng, Jie; Zhang, Gui-Juan; Jiang, Xiao-Ling; Cheng, Jing; Chen, Huan; Jiang, Zhi-Gang; Xu, De-Lin; He, Yi-Huai

Feedback loop between hepatocyte nuclear factor 1α and endoplasmic reticulum stress mitigates liver injury by downregulating hepatocyte apoptosis.

Liu, Si-Ying; Rao, Jian-Xu; Deng, Jie; Zhang, Gui-Juan; Jiang, Xiao-Ling; Cheng, Jing; Chen, Huan; Jiang, Zhi-Gang; Xu, De-Lin; He, Yi-Huai.

Afiliación

Liu SY; Department of Infectious Diseases, The Affiliated Hospital of Zunyi Medical University, No. 201 Dalian Street, Zunyi, 563000, Guizhou, China.
Rao JX; Department of Infectious Diseases, The Affiliated Hospital of Zunyi Medical University, No. 201 Dalian Street, Zunyi, 563000, Guizhou, China.
Deng J; Department of Infectious Diseases, The Affiliated Hospital of Zunyi Medical University, No. 201 Dalian Street, Zunyi, 563000, Guizhou, China.
Zhang GJ; Department of Infectious Diseases, The Affiliated Hospital of Zunyi Medical University, No. 201 Dalian Street, Zunyi, 563000, Guizhou, China.
Jiang XL; Department of Infectious Diseases, The Affiliated Hospital of Zunyi Medical University, No. 201 Dalian Street, Zunyi, 563000, Guizhou, China.
Cheng J; Department of Infectious Diseases, The Affiliated Hospital of Zunyi Medical University, No. 201 Dalian Street, Zunyi, 563000, Guizhou, China.
Chen H; Department of Infectious Diseases, The Affiliated Hospital of Zunyi Medical University, No. 201 Dalian Street, Zunyi, 563000, Guizhou, China.
Jiang ZG; School of Public Health, Zunyi Medical University, Zunyi, 563099, Guizhou, China.
Xu DL; Cell Biology Department, Zunyi Medical University, Zunyi, 563099, Guizhou, China.
He YH; Department of Infectious Diseases, The Affiliated Hospital of Zunyi Medical University, No. 201 Dalian Street, Zunyi, 563000, Guizhou, China. 993565989@qq.com.

Sci Rep ; 12(1): 11602, 2022 07 08.

Article en En | MEDLINE | ID: mdl-35804081

Asunto(s)

Estrés del Retículo Endoplásmico; Factor Nuclear 1-alfa del Hepatocito; Factor de Transcripción Activador 4/metabolismo; Animales; Apoptosis; Estrés del Retículo Endoplásmico/fisiología; Retroalimentación; Factor Nuclear 1-alfa del Hepatocito/metabolismo; Hepatocitos/metabolismo; Humanos; Lipopolisacáridos/metabolismo; Hígado/metabolismo; Ratones; FN-kappa B/metabolismo

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor Nuclear 1-alfa del Hepatocito / Estrés del Retículo Endoplásmico Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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