Copper-assisted trifluoromethylthiolation/radical cascade cyclization of alkynes to construct SCF3-containing dioxodibenzothiazepines.
Chem Commun (Camb)
; 58(62): 8674-8677, 2022 Aug 02.
Article
en En
| MEDLINE
| ID: mdl-35822922
ABSTRACT
A mild and efficient Cu-assisted trifluoromethylthiolation/radical cascade cyclization of alkynes with readily available and stable AgSCF3 as the trifluoromethylthiolating reagent has been disclosed. This transformation provides an opportunity to construct a series of potential medicinally valuable trifluoromethylthio-substituted dioxodibenzothiazepines with wide functional group compatibility. This protocol opens up a new avenue for the construction of useful trifluoromethylthiolated seven-membered N-heterocycles.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cobre
/
Alquinos
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2022
Tipo del documento:
Article