Synthesis of multifunctional crown ether covalent organic nanospheres as stationary phase for capillary electrochromatography.
J Chromatogr A
; 1677: 463323, 2022 Aug 16.
Article
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| MEDLINE
| ID: mdl-35853421
ABSTRACT
Crown ethers are macrocyclic polyether compounds containing multiple -oxo-methylene-structural units, which are often used for recognition of metal ions and ammonium ions. Inspired by the molecular design of rotaxanes, a novel covalent organic nanospheres material (CON ADBC-Tp) constructed by 4,4'-diaminodibenzo-18-crown-6 (ADBC) and 2,4,6-triformylphloroglucinol (Tp) was rationally designed as stationary phase for the separation of compounds containing imidazole structure. Scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FT-IR) were carried out to confirm the morphology and composition of ADBC-Tp and ADBC-Tp modified capillary column. Thanks to the introduction of crown ether building ligands, the prepared capillary column exhibited excellent separation selectivity towards protonated imidazole structure, with benzimidazole and its 2-substituted derivatives as modal analytes. Moreover, separation of fungicides, nucleobases, short peptides and sulfanilamides were achieved on ADBC-Tp@capillary. The multifunctional ADBC-Tp@capillary with satisfactory reproducibility and stability gives great promise for separation science.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Éteres Corona
/
Electrocromatografía Capilar
/
Nanosferas
Idioma:
En
Revista:
J Chromatogr A
Año:
2022
Tipo del documento:
Article