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Scaffolding protein functional sites using deep learning.
Wang, Jue; Lisanza, Sidney; Juergens, David; Tischer, Doug; Watson, Joseph L; Castro, Karla M; Ragotte, Robert; Saragovi, Amijai; Milles, Lukas F; Baek, Minkyung; Anishchenko, Ivan; Yang, Wei; Hicks, Derrick R; Expòsit, Marc; Schlichthaerle, Thomas; Chun, Jung-Ho; Dauparas, Justas; Bennett, Nathaniel; Wicky, Basile I M; Muenks, Andrew; DiMaio, Frank; Correia, Bruno; Ovchinnikov, Sergey; Baker, David.
Afiliación
  • Wang J; Department of Biochemistry, University of Washington, Seattle, WA 98105, USA.
  • Lisanza S; Institute for Protein Design, University of Washington, Seattle, WA 98105, USA.
  • Juergens D; Department of Biochemistry, University of Washington, Seattle, WA 98105, USA.
  • Tischer D; Institute for Protein Design, University of Washington, Seattle, WA 98105, USA.
  • Watson JL; Graduate Program in Biological Physics, Structure and Design, University of Washington, Seattle, WA 98105, USA.
  • Castro KM; Department of Biochemistry, University of Washington, Seattle, WA 98105, USA.
  • Ragotte R; Institute for Protein Design, University of Washington, Seattle, WA 98105, USA.
  • Saragovi A; Molecular Engineering Graduate Program, University of Washington, Seattle, WA 98105, USA.
  • Milles LF; Department of Biochemistry, University of Washington, Seattle, WA 98105, USA.
  • Baek M; Institute for Protein Design, University of Washington, Seattle, WA 98105, USA.
  • Anishchenko I; Department of Biochemistry, University of Washington, Seattle, WA 98105, USA.
  • Yang W; Institute for Protein Design, University of Washington, Seattle, WA 98105, USA.
  • Hicks DR; Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, Switzerland.
  • Expòsit M; Department of Biochemistry, University of Washington, Seattle, WA 98105, USA.
  • Schlichthaerle T; Institute for Protein Design, University of Washington, Seattle, WA 98105, USA.
  • Chun JH; Department of Biochemistry, University of Washington, Seattle, WA 98105, USA.
  • Dauparas J; Institute for Protein Design, University of Washington, Seattle, WA 98105, USA.
  • Bennett N; Department of Biochemistry, University of Washington, Seattle, WA 98105, USA.
  • Wicky BIM; Institute for Protein Design, University of Washington, Seattle, WA 98105, USA.
  • Muenks A; Department of Biochemistry, University of Washington, Seattle, WA 98105, USA.
  • DiMaio F; Institute for Protein Design, University of Washington, Seattle, WA 98105, USA.
  • Correia B; Department of Biochemistry, University of Washington, Seattle, WA 98105, USA.
  • Ovchinnikov S; Institute for Protein Design, University of Washington, Seattle, WA 98105, USA.
  • Baker D; Department of Biochemistry, University of Washington, Seattle, WA 98105, USA.
Science ; 377(6604): 387-394, 2022 07 22.
Article en En | MEDLINE | ID: mdl-35862514
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ingeniería de Proteínas / Proteínas / Aprendizaje Profundo Idioma: En Revista: Science Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ingeniería de Proteínas / Proteínas / Aprendizaje Profundo Idioma: En Revista: Science Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos