Vaccination of young lambs by means of a protein fraction extracted from adult Haemonchus contortus.
Parasitology
; 94 ( Pt 2): 385-97, 1987 Apr.
Article
en En
| MEDLINE
| ID: mdl-3588016
ABSTRACT
Lambs aged 48-150 days which had been injected with extracts enriched in a functional antigen (contortin) obtained from adult Haemonchus contortus developed specific circulating antibodies and were less susceptible to haemonchosis when challenged 1 month later with a single dose of 20,000-25,000 infective 3rd-stage larvae. Sera from 18 out of a total of 19 lambs injected with the extract contained precipitating antibodies to 2-5 components of the extract. None of these lambs died. The one extract-injected lamb which did not develop antibodies and 9 of the 13 lambs used as controls died of haemonchosis. The average weight of worms recovered was 1.45 g from the immune lambs and 5.72 g from the non-immune lambs.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades de las Ovejas
/
Trichostrongyloidea
/
Tricostrongiloidiasis
/
Vacunas
/
Hemoncosis
/
Haemonchus
/
Antígenos Helmínticos
Límite:
Animals
Idioma:
En
Revista:
Parasitology
Año:
1987
Tipo del documento:
Article