Atherosclerosis Plaque Reduction by Lycopene Is Mediated by Increased Energy Expenditure through AMPK and PPAR&#945; in ApoE KO Mice Fed with a High Fat Diet.

Mannino, Federica; Pallio, Giovanni; Altavilla, Domenica; Squadrito, Francesco; Vermiglio, Giovanna; Bitto, Alessandra; Irrera, Natasha

Atherosclerosis Plaque Reduction by Lycopene Is Mediated by Increased Energy Expenditure through AMPK and PPARα in ApoE KO Mice Fed with a High Fat Diet.

Mannino, Federica; Pallio, Giovanni; Altavilla, Domenica; Squadrito, Francesco; Vermiglio, Giovanna; Bitto, Alessandra; Irrera, Natasha.

Afiliación

Mannino F; Department of Clinical and Experimental Medicine, University of Messina, Via C. Valeria, 98125 Messina, Italy.
Pallio G; Department of Clinical and Experimental Medicine, University of Messina, Via C. Valeria, 98125 Messina, Italy.
Altavilla D; Department of Biomedical, Dental, Morphological and Functional Imaging Sciences, University of Messina, Via C. Valeria, 98125 Messina, Italy.
Squadrito F; SunNutraPharma s.r.l., Spin-Off Company of University of Messina, Via C. Valeria, 98125 Messina, Italy.
Vermiglio G; Department of Clinical and Experimental Medicine, University of Messina, Via C. Valeria, 98125 Messina, Italy.
Bitto A; SunNutraPharma s.r.l., Spin-Off Company of University of Messina, Via C. Valeria, 98125 Messina, Italy.
Irrera N; Department of Biomedical, Dental, Morphological and Functional Imaging Sciences, University of Messina, Via C. Valeria, 98125 Messina, Italy.

Biomolecules ; 12(7)2022 07 12.

Article en En | MEDLINE | ID: mdl-35883529

Asunto(s)

Aterosclerosis; Placa Aterosclerótica; Proteínas Quinasas Activadas por AMP/metabolismo; Animales; Antioxidantes/metabolismo; Antioxidantes/farmacología; Apolipoproteínas E/genética; Apolipoproteínas E/metabolismo; Aterosclerosis/metabolismo; Grosor Intima-Media Carotídeo; Dieta Alta en Grasa/efectos adversos; Metabolismo Energético; Humanos; Licopeno/farmacología; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; PPAR alfa/metabolismo; Placa Aterosclerótica/metabolismo

Palabras clave

PPARα; atherosclerosis; lycopene; nutraceuticals; oxidative stress

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aterosclerosis / Placa Aterosclerótica Tipo de estudio: Health_economic_evaluation / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Biomolecules Año: 2022 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza

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