Further insights into the impact of rebamipide on gentamicin-induced nephrotoxicity in rats: modulation of SIRT1 and ß-catenin/cyclin D1 pathways.

Zaky, Heba S; Abdel-Sattar, Somaia A; Allam, Albatoul; Ahmed, Hebatalla I

Zaky, Heba S; Abdel-Sattar, Somaia A; Allam, Albatoul; Ahmed, Hebatalla I.

Afiliación

Zaky HS; Department of Pharmacology and Toxicology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
Abdel-Sattar SA; Department of Pharmacology and Toxicology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
Allam A; Department of Pharmacology and Toxicology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.
Ahmed HI; Department of Pharmacology and Toxicology, Faculty of Pharmacy (Girls), Al-Azhar University, Cairo, Egypt.

Drug Chem Toxicol ; 46(5): 851-863, 2023 Nov.

Article en En | MEDLINE | ID: mdl-35899710

Asunto(s)

Gentamicinas; Sirtuina 1; Ratas; Animales; Gentamicinas/toxicidad; Gentamicinas/metabolismo; Sirtuina 1/metabolismo; Sirtuina 1/farmacología; Ciclina D1/metabolismo; beta Catenina/metabolismo; beta Catenina/farmacología; Riñón; Proteínas Proto-Oncogénicas c-bcl-2/metabolismo; Estrés Oxidativo; FN-kappa B/metabolismo; FN-kappa B/farmacología; Factor 2 Relacionado con NF-E2/metabolismo

Palabras clave

Gentamicin; SIRT1; nephrotoxicity; rats; rebamipide; ß-catenin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Gentamicinas / Sirtuina 1 Límite: Animals Idioma: En Revista: Drug Chem Toxicol Año: 2023 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Estados Unidos

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