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Circulating short-chain fatty acids in type 2 diabetic patients and overweight/obese individuals.
Salamone, Dominic; Costabile, Giuseppina; Corrado, Alessandra; Della Pepa, Giuseppe; Vitale, Marilena; Giacco, Rosalba; Luongo, Delia; Testa, Roberta; Rivellese, Angela Albarosa; Annuzzi, Giovanni; Bozzetto, Lutgarda.
Afiliación
  • Salamone D; Department of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy.
  • Costabile G; Department of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy.
  • Corrado A; Task Force on Microbiome Studies, University of Naples "Federico II", Naples, Italy.
  • Della Pepa G; Department of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy.
  • Vitale M; Department of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy.
  • Giacco R; Department of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy.
  • Luongo D; Institute of Food Science, National Research Council, 83100, Avellino, Italy.
  • Testa R; CNR- Institute of Biostructures and Bioimaging, 80100, Naples, Italy.
  • Rivellese AA; Department of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy.
  • Annuzzi G; Department of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy. rivelles@unina.it.
  • Bozzetto L; Task Force on Microbiome Studies, University of Naples "Federico II", Naples, Italy. rivelles@unina.it.
Acta Diabetol ; 59(12): 1653-1656, 2022 Dec.
Article en En | MEDLINE | ID: mdl-35920899
ABSTRACT

AIM:

aim of the study was to evaluate serum short chain fatty acids (SCFA) concentrations in patients with Type 2 diabetes (T2D) and overweight/obese individuals.

METHODS:

In forty-three patients with T2D and twenty-eight overweight/obese patients SCFA were determined by Gas-Chromatography/Flame Ionization Detector (GC/FID).

RESULTS:

Acetic acid, propionic acid, butyric acid, and total SCFA were significantly reduced in T2D patients compared to overweight/obese in the unadjusted model. Adjusting for all variables only propionic acid remained significantly lower in T2D.

CONCLUSION:

Only reduction of propionic acid was closely related to diabetes itself, regardless of all other factors.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Propionatos / Diabetes Mellitus Tipo 2 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Acta Diabetol Asunto de la revista: ENDOCRINOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Italia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Propionatos / Diabetes Mellitus Tipo 2 Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Acta Diabetol Asunto de la revista: ENDOCRINOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Italia