Circulating short-chain fatty acids in type 2 diabetic patients and overweight/obese individuals.
Acta Diabetol
; 59(12): 1653-1656, 2022 Dec.
Article
en En
| MEDLINE
| ID: mdl-35920899
ABSTRACT
AIM:
aim of the study was to evaluate serum short chain fatty acids (SCFA) concentrations in patients with Type 2 diabetes (T2D) and overweight/obese individuals.METHODS:
In forty-three patients with T2D and twenty-eight overweight/obese patients SCFA were determined by Gas-Chromatography/Flame Ionization Detector (GC/FID).RESULTS:
Acetic acid, propionic acid, butyric acid, and total SCFA were significantly reduced in T2D patients compared to overweight/obese in the unadjusted model. Adjusting for all variables only propionic acid remained significantly lower in T2D.CONCLUSION:
Only reduction of propionic acid was closely related to diabetes itself, regardless of all other factors.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Propionatos
/
Diabetes Mellitus Tipo 2
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Acta Diabetol
Asunto de la revista:
ENDOCRINOLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Italia