[Toll-like receptors link atopic march and hygiene hypothesis].
Zhonghua Jie He He Hu Xi Za Zhi
; 45(8): 803-808, 2022 Aug 12.
Article
en Zh
| MEDLINE
| ID: mdl-35927050
ABSTRACT
The atopic march reveals that infants with atopic dermatitis are prone to food allergy, allergic rhinitis and asthma later in life. The hygiene hypothesis holds that the cleaner the personal hygiene and environment, the higher the incidence rate of asthma and allergy. It is believed that Toll like receptors (TLRs) are the bridge between innate immunity and adaptive immunity, playing an important role in inflammatory and immune diseases. More and more evidence shows that TLRs, involved in the pathophysiology of atopic march, connect atopic march with hygiene hypothesis as a potential therapeutic target for asthma and allergy.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Asma
/
Dermatitis Atópica
/
Rinitis Alérgica
Límite:
Humans
Idioma:
Zh
Revista:
Zhonghua Jie He He Hu Xi Za Zhi
Año:
2022
Tipo del documento:
Article
País de afiliación:
China