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Engineered DNA-encoded monoclonal antibodies targeting Plasmodium falciparum circumsporozoite protein confer single dose protection in a murine malaria challenge model.
Tursi, Nicholas J; Reeder, Sophia M; Flores-Garcia, Yevel; Bah, Mamadou A; Mathis-Torres, Shamika; Salgado-Jimenez, Berenice; Esquivel, Rianne; Xu, Ziyang; Chu, Jacqueline D; Humeau, Laurent; Patel, Ami; Zavala, Fidel; Weiner, David B.
Afiliación
  • Tursi NJ; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
  • Reeder SM; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Flores-Garcia Y; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
  • Bah MA; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Mathis-Torres S; Department of Molecular Microbiology and Immunology, Malaria Research Institute, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, 21205, USA.
  • Salgado-Jimenez B; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
  • Esquivel R; Department of Molecular Microbiology and Immunology, Malaria Research Institute, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, 21205, USA.
  • Xu Z; Department of Molecular Microbiology and Immunology, Malaria Research Institute, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, 21205, USA.
  • Chu JD; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
  • Humeau L; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
  • Patel A; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Zavala F; Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA, 19104, USA.
  • Weiner DB; Inovio Pharmaceuticals, Plymouth Meeting, PA, 19462, USA.
Sci Rep ; 12(1): 14313, 2022 08 22.
Article en En | MEDLINE | ID: mdl-35995959
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Malaria Falciparum / Vacunas contra la Malaria / Anticuerpos Monoclonales Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Malaria Falciparum / Vacunas contra la Malaria / Anticuerpos Monoclonales Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido