Concordance for Gender Dysphoria in Genetic Female Monozygotic (Identical) Triplets.
Arch Sex Behav
; 51(7): 3647-3651, 2022 Oct.
Article
en En
| MEDLINE
| ID: mdl-36044128
ABSTRACT
The biopsychosocial etiology of gender dysphoria is poorly understood, but current thought suggests a complex interaction of genetic, hormonal, environmental, and differences in brain development and physiology. Twin studies have implicated a genetic role in the formation of gender identity. Congruence for gender dysphoria is more common among monozygotic twins compared to dizygotic twins. We present a case of monozygotic (identical) triplets who have each transitioned from female to male under the care of a university transgender health service. Each triplet experienced gender dysphoria from childhood and has undergone transitional endocrine care and various aspects of gender-affirming surgery. Although a pure genetic or biological component cannot be attributed as a cause of their gender dysphoria with absolute certainty since the triplets were raised together, this unusual case of gender dysphoria among a set of monozygotic triplets adds support for a heritable role in gender identity formation.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Personas Transgénero
/
Disforia de Género
Aspecto:
Determinantes_sociais_saude
Límite:
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Arch Sex Behav
Año:
2022
Tipo del documento:
Article
País de afiliación:
Estados Unidos