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Hydrogen Transfer Coupling with 100% Atom Economy: Synthesis of 2-Indolyltetrahydronaphthyridine Derivatives.
Zeng, Zheng; Deng, Yiqiu; Li, Lanyu; Li, Chungang; Zhong, Mingli.
Afiliación
  • Zeng Z; Affiliated Hospital of Guilin Medical University, Guilin 541001, China.
  • Deng Y; Affiliated Hospital of Guilin Medical University, Guilin 541001, China.
  • Li L; College of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou 310023, Zhejiang, China.
  • Li C; Affiliated Hospital of Guilin Medical University, Guilin 541001, China.
  • Zhong M; The 926th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army, Kaiyuan 661600, Yunnan, China.
J Org Chem ; 87(18): 12257-12264, 2022 09 16.
Article en En | MEDLINE | ID: mdl-36045006
ABSTRACT
An iridium-catalyzed hydrogen transfer strategy, enabling straightforward access to tetrahydropyridine derivatives from aryl-1,8-naphthyridines and indolines was developed. This method has unprecedented advantages, including high step economy. In addition, it does not produce any byproducts or require an external high-pressure H2 gas source. The method offers an important platform for the transformation of 1,8-naphthyridines and indolines into functionalized products.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hidrógeno / Iridio Tipo de estudio: Health_economic_evaluation Idioma: En Revista: J Org Chem Año: 2022 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hidrógeno / Iridio Tipo de estudio: Health_economic_evaluation Idioma: En Revista: J Org Chem Año: 2022 Tipo del documento: Article País de afiliación: China