KRIT1: A Traffic Warden at the Busy Crossroads Between Redox Signaling and the Pathogenesis of Cerebral Cavernous Malformation Disease.

Perrelli, Andrea; Ferraris, Chiara; Berni, Elisa; Glading, Angela J; Retta, Saverio Francesco

Perrelli, Andrea; Ferraris, Chiara; Berni, Elisa; Glading, Angela J; Retta, Saverio Francesco.

Afiliación

Perrelli A; Department of Clinical and Biological Sciences, University of Torino, Torino, Italy.
Ferraris C; CCM Italia Research Network, National Coordination Center at the Department of Clinical and Biological Sciences, University of Torino, Torino, Italy.
Berni E; Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, New York, USA.
Glading AJ; Department of Clinical and Biological Sciences, University of Torino, Torino, Italy.
Retta SF; CCM Italia Research Network, National Coordination Center at the Department of Clinical and Biological Sciences, University of Torino, Torino, Italy.

Antioxid Redox Signal ; 38(7-9): 496-528, 2023 03.

Article en En | MEDLINE | ID: mdl-36047808

Asunto(s)

Hemangioma Cavernoso del Sistema Nervioso Central; Humanos; Hemangioma Cavernoso del Sistema Nervioso Central/genética; Hemangioma Cavernoso del Sistema Nervioso Central/metabolismo; Células Endoteliales/metabolismo; Transducción de Señal; Oxidación-Reducción; Inflamación; Proteínas Asociadas a Microtúbulos/metabolismo; Proteína KRIT1/metabolismo

Palabras clave

GTPases; KRIT1; MAPKs; NADPH oxidases; cerebral cavernous malformation (CCM); cerebrovascular disease; endothelial cell adhesion and barrier function; endothelial-to-mesenchymal transition (EndMT); inflammation; oxidative post-translational modifications (Ox-PTMs); oxidative stress; reactive oxygen species (ROS); redox homeostasis and signaling

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hemangioma Cavernoso del Sistema Nervioso Central Tipo de estudio: Etiology_studies Límite: Humans Idioma: En Revista: Antioxid Redox Signal Asunto de la revista: METABOLISMO Año: 2023 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos

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