Molecular docking, synthesis, and biological evaluation of 7-azaindole-derivative (7AID) as novel anti-cancer agent and potent DDX3 inhibitor:-an in silico and in vitro approach.

Doneti, Ravinder; Pasha, Akbar; Botlagunta, Mahendran; Heena, S K; Mutyala, Veera Venkata Vara Prasad; Pawar, Smita C

Doneti, Ravinder; Pasha, Akbar; Botlagunta, Mahendran; Heena, S K; Mutyala, Veera Venkata Vara Prasad; Pawar, Smita C.

Afiliación

Doneti R; Department of Genetics & Biotechnology, Osmania University, Hyderabad, Telangana, 500 007, India.
Pasha A; Department of Genetics & Biotechnology, Osmania University, Hyderabad, Telangana, 500 007, India.
Botlagunta M; School of Biosciences Engineering and Technology, VIT Bhopal University, Bhopal, Madhya Pradesh, 466114, India.
Heena SK; Department of Pathology, Osmania Medical College, Hyderabad, Telangana, 500095, India.
Mutyala VVVP; Department of Chemistry, T John Institute of Technology, Bangalore, Karnataka, 560076, India.
Pawar SC; Department of Genetics & Biotechnology, Osmania University, Hyderabad, Telangana, 500 007, India. dr.smitapawar@osmania.ac.in.

Med Oncol ; 39(11): 179, 2022 Sep 01.

Article en En | MEDLINE | ID: mdl-36048256

Asunto(s)

ARN Helicasas DEAD-box; Línea Celular Tumoral; Proliferación Celular; ARN Helicasas DEAD-box/metabolismo; Células HeLa; Humanos; Indoles; Simulación del Acoplamiento Molecular; ARN Mensajero

Palabras clave

Anti-angiogenic; Anti-cancer; CAM assay; Cytotoxicity; DDX3; Immunohistochemistry; Wound healing

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: ARN Helicasas DEAD-box Límite: Humans Idioma: En Revista: Med Oncol Asunto de la revista: NEOPLASIAS Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Estados Unidos

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