Your browser doesn't support javascript.
loading
Treatment outcome, cognitive function, and psychopathology in methamphetamine users compared to other substance users.
Behle, Nina; Kamp, Felicia; Proebstl, Lisa; Hager, Laura; Riebschläger, Marlies; Schacht-Jablonowsky, Maik; Hamdorf, Willem; Neumann, Stefanie; Krause, Daniela; Manz, Kirsi; Franke, Andreas Guenter; Koller, Gabriele; Soyka, Michael.
Afiliación
  • Behle N; Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich 80336, Germany.
  • Kamp F; Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich 80336, Germany.
  • Proebstl L; Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich 80336, Germany.
  • Hager L; Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich 80336, Germany.
  • Riebschläger M; MEDIAN Clinic, Mecklenburg, Vitense 19217, Germany.
  • Schacht-Jablonowsky M; MEDIAN Clinic, Mecklenburg, Vitense 19217, Germany.
  • Hamdorf W; MEDIAN Clinic, Mecklenburg, Vitense 19217, Germany.
  • Neumann S; MEDIAN Clinic, Mecklenburg, Vitense 19217, Germany.
  • Krause D; Department of Psychiatry and Psychotherapy, Ludwig Maximilians University, Munich 80336, Germany.
  • Manz K; Institute for Medical Information Processing, Ludwig Maximilians University, Munich 81377, Germany.
  • Franke AG; University of Applied Labour Studies of the Federal Employment Agency, Mannheim 68163, Germany.
  • Koller G; Department of Psychiatry, Ludwig Maximilians University, Munich 80336, Germany. gabi.koller@med.uni-muenchen.de.
  • Soyka M; Department of Psychiatry, Ludwig Maximilians University, Munich 80336, Germany.
World J Psychiatry ; 12(7): 944-957, 2022 Jul 19.
Article en En | MEDLINE | ID: mdl-36051595
ABSTRACT

BACKGROUND:

The rising number of people using methamphetamine leads to an increasing need for treatment options for this patient group. Evidence-based research on the efficacy of treatment programs for methamphetamine users is limited. Due to specific characteristics of methamphetamine users, the question arises whether established treatment methods for individuals using other substances can be effective for the treatment of methamphetamine dependence as well. We hypothesize that there are significant differences between the two groups that may affect the effectiveness of treatment and worsen the prognosis of treatment outcomes for methamphetamine users compared to consumers of other substances.

AIM:

To investigate potential differences in cognitive functioning and psychopathology between methamphetamine users and other substance users and possible correlations with treatment outcomes.

METHODS:

A total of 110 subjects were recruited for an observational, longitudinal study from a German inpatient addiction treatment center 55 patients with methamphetamine dependence and 55 patients with dependence of other substances ("OS group"). Both groups were examined at beginning (baseline) and end of treatment (after 6 mo) with regard to treatment retention, craving, cognitive functioning, psychosocial resources, personality traits, depression, and other psychiatric symptoms. Instruments used were Raven's IQ test, Mannheimer craving scale, cognitrone cognitive test battery, NEO personality factors inventory, Hamilton depression scale, Becks depression inventory, and a symptom checklist. The statistical methods used were χ 2-test, t-test and multiple mixed ANOVAs.

RESULTS:

A total drop-out rate of 40% (methamphetamine-group 36.4%; OS-group 43.6%) was observed without significant differences between groups. At baseline, methamphetamine-group subjects significantly differed from OS-group individuals in terms of a lower intelligence quotient, fewer years of education, slower working speed, and decreased working accuracy, as well as less cannabinoid and cocaine use. Methamphetamine-group subjects further showed a significantly lower score of conscientiousness, depressive, and psychiatric symptoms than subjects from the OS-group. In both groups, a reduction of craving and depressive symptoms and an improvement of working speed and working accuracy was noted after treatment.

CONCLUSION:

There are differences between methamphetamine users and users of other drugs, but not with regard to the effectiveness of treatment in this inpatient setting. There are differences in cognitive function and psychopathology between methamphetamine and other drugs users. The existing treatment options seem to be an effective approach in treating methamphetamine dependence.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Prognostic_studies Idioma: En Revista: World J Psychiatry Año: 2022 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Prognostic_studies Idioma: En Revista: World J Psychiatry Año: 2022 Tipo del documento: Article País de afiliación: Alemania