Direct Laser 3D Printing of Organic Semiconductor Microdevices for Bioelectronics and Biosensors.
Annu Int Conf IEEE Eng Med Biol Soc
; 2022: 1569-1572, 2022 07.
Article
en En
| MEDLINE
| ID: mdl-36085618
ABSTRACT
Fabrication of conductive and bioactive microdevices has garnered tremendous attention in the emerging biomedical fields, particularly organic bioelectronics and biosensing. Direct laser 3D printing based on two-photon polymerization (TPP) has shown great promise in construction of well-defined and multi-functional microdevices. Herein, we present a novel photosensitive resin for fabrication of highly conductive and bioactive microstructures via TPP. This resin is based on poly(ethylene glycol) diacrylate that is doped with poly (3,4-ethylenedioxythiophene)-poly(styrenesulfonate) (organic semicoductor), and laminin (extracellular matrix protein) or glucose oxidase (biorecognition enzyme). We demonstrate the fabrication of hybrid microelectrodes, bioactive microstructures for cellular adhesion / spreading, and high-performance glucose biosensors. Clinical Relevance- Conductive and bioactive microelectronic devices based on the formulated resin can be utilized for neural recording / stimulation, tissue engineering, and biosensing applications.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Semiconductores
/
Técnicas Biosensibles
Idioma:
En
Revista:
Annu Int Conf IEEE Eng Med Biol Soc
Año:
2022
Tipo del documento:
Article