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Triterpene constituents from the fruits of Cyclocarya paliurus and their anti-HIV-1IIIB activity.
Tu, Wen-Chao; Luo, Rong-Hua; Yuan, En; Sakah, Kaunda-Joseph; Yang, Quan-Yu; Xiao, Wei-Lie; Zheng, Yong-Tang; Liu, Mei-Feng.
Afiliación
  • Tu WC; Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, China.
  • Luo RH; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education; Yunnan Provincial Center for Research & Development of Natural Products; School of Chemical Science and Technology, Yunnan University, Kunming, China.
  • Yuan E; Key Laboratory of Bioactive Peptides of Yunnan Province & Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
  • Sakah KJ; Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, China.
  • Yang QY; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education; Yunnan Provincial Center for Research & Development of Natural Products; School of Chemical Science and Technology, Yunnan University, Kunming, China.
  • Xiao WL; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education; Yunnan Provincial Center for Research & Development of Natural Products; School of Chemical Science and Technology, Yunnan University, Kunming, China.
  • Zheng YT; Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education; Yunnan Provincial Center for Research & Development of Natural Products; School of Chemical Science and Technology, Yunnan University, Kunming, China.
  • Liu MF; Key Laboratory of Bioactive Peptides of Yunnan Province & Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
Nat Prod Res ; 37(11): 1787-1796, 2023 Jun.
Article en En | MEDLINE | ID: mdl-36095038
Four new norceanothane-type triterpenes, cyclopalin A-D (1-4), and sixteen known compounds (5-20) were obtained from the fruits of Cyclocarya paliurus. Their structures were determined by spectroscopic data, experimental electronic circular dichroism (ECD) and X-ray single crystal analyses. All isolated compounds were assayed for their anti-HIV-1IIIB activity. Compound 18 exhibited potent anti-HIV-1IIIB activity with an EC50 value of 1.32 µM (SI = 151.52).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triterpenos / Juglandaceae Idioma: En Revista: Nat Prod Res Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triterpenos / Juglandaceae Idioma: En Revista: Nat Prod Res Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido