Intracerebroventricular administration of oxytocin and intranasal administration of the oxytocin derivative improve ß-amyloid peptide (25-35)-induced memory impairment in mice.

Takahashi, Junpei; Ueta, Yudai; Yamada, Daisuke; Sasaki-Hamada, Sachie; Iwai, Takashi; Akita, Tomomi; Yamashita, Chikamasa; Saitoh, Akiyoshi; Oka, Jun-Ichiro

Takahashi, Junpei; Ueta, Yudai; Yamada, Daisuke; Sasaki-Hamada, Sachie; Iwai, Takashi; Akita, Tomomi; Yamashita, Chikamasa; Saitoh, Akiyoshi; Oka, Jun-Ichiro.

Afiliación

Takahashi J; Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
Ueta Y; Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
Yamada D; Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
Sasaki-Hamada S; Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
Iwai T; Department of Physiology, School of Allied Health Sciences, Kitasato University, Sagamihara, Japan.
Akita T; Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
Yamashita C; Laboratory of Pharmacology, School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan.
Saitoh A; Laboratory of Pharmaceutics and Drug Delivery, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.
Oka JI; Laboratory of Pharmaceutics and Drug Delivery, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan.

Neuropsychopharmacol Rep ; 42(4): 492-501, 2022 12.

Article en En | MEDLINE | ID: mdl-36117475

Asunto(s)

Enfermedad de Alzheimer; Péptidos beta-Amiloides; Ratones; Animales; Oxitocina/efectos adversos; Administración Intranasal; Trastornos de la Memoria/inducido químicamente; Trastornos de la Memoria/tratamiento farmacológico; Enfermedad de Alzheimer/inducido químicamente; Enfermedad de Alzheimer/tratamiento farmacológico

Palabras clave

amnesia; brain drug delivery and targeting; intranasal administration; oxytocin; spatial memory; ß-amyloid peptide (25-35)

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos beta-Amiloides / Enfermedad de Alzheimer Límite: Animals Idioma: En Revista: Neuropsychopharmacol Rep Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

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