Vonoprazan in the management of erosive oesophagitis and peptic ulcer-induced medication: a systematic review.
Prz Gastroenterol
; 17(3): 183-189, 2022.
Article
en En
| MEDLINE
| ID: mdl-36127938
ABSTRACT
Introduction:
Vonoprazan has been found to promote a better antisecretory effect addressing acid-related diseases' unmet needs.Aim:
To assess if vonoprazan effectively treats patients diagnosed with gastroesophageal reflux disease esophagitis or with peptic ulcers induced by chronic use of aspirin or non-steroidal anti-inflammatory drugs. Material andmethods:
A literature search was conducted (April/2021) using Medline via PubMed, Cochrane library, Lilacs, Scielo, and Centre for Reviews and Dissemination electronic databases.Results:
We retrieved 55 titles. Of these, 13 met the eligibility criteria and were included in this review. Of these 13 articles, 4 were prospective cohort studies, 1 was a follow-up analysis of a preceding prospective study, 1 was a retrospective cohort study, and 6 were randomized clinical trials.Conclusions:
Our findings suggest that vonoprazan was effective and non-inferior to proton pump inhibitors in healing and maintaining healed reflux oesophagitis, leading to faster symptom relief. Vonoprazan may also be considered for preventing aspirin- or non-steroidal anti-inflammatory drug-related peptic ulcer recurrence.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Clinical_trials
/
Observational_studies
/
Systematic_reviews
Idioma:
En
Revista:
Prz Gastroenterol
Año:
2022
Tipo del documento:
Article
País de afiliación:
Brasil