Examination of Longitudinal Alterations in Alzheimer's Disease-Related Neurogenesis in an APP/PS1 Transgenic Mouse Model, and the Effects of P33, a Putative Neuroprotective Agent Thereon.

Szögi, Titanilla; Borbély, Emoke; Schuster, Ildikó; Bozsó, Zsolt; Sántha, Miklós; Tóth, Melinda E; Penke, Botond; Fülöp, Lívia

Szögi, Titanilla; Borbély, Emoke; Schuster, Ildikó; Bozsó, Zsolt; Sántha, Miklós; Tóth, Melinda E; Penke, Botond; Fülöp, Lívia.

Afiliación

Szögi T; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
Borbély E; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
Schuster I; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
Bozsó Z; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
Sántha M; Institute of Biochemistry, Biological Research Centre, Temesvári Krt. 62., H-6726 Szeged, Hungary.
Tóth ME; Institute of Biochemistry, Biological Research Centre, Temesvári Krt. 62., H-6726 Szeged, Hungary.
Penke B; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
Fülöp L; Department of Medical Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.

Int J Mol Sci ; 23(18)2022 Sep 08.

Article en En | MEDLINE | ID: mdl-36142277

Asunto(s)

Enfermedad de Alzheimer; Fármacos Neuroprotectores; Enfermedad de Alzheimer/tratamiento farmacológico; Enfermedad de Alzheimer/genética; Enfermedad de Alzheimer/metabolismo; Péptidos beta-Amiloides/farmacología; Precursor de Proteína beta-Amiloide/genética; Precursor de Proteína beta-Amiloide/metabolismo; Animales; Modelos Animales de Enfermedad; Humanos; Lactante; Ratones; Ratones Endogámicos C57BL; Ratones Transgénicos; Neurogénesis; Fármacos Neuroprotectores/farmacología; Fármacos Neuroprotectores/uso terapéutico; Presenilina-1/genética; Presenilina-1/metabolismo

Palabras clave

APP/PS1 mice; Alzheimer's disease; P33; neurogenesis; neuroinflammation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fármacos Neuroprotectores / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Infant Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Hungria

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