Structure and Function of Mycobacterial Arabinofuranosyltransferases.
Subcell Biochem
; 99: 379-391, 2022.
Article
en En
| MEDLINE
| ID: mdl-36151383
ABSTRACT
The mycobacteria genus is responsible for numerous infectious diseases that have afflicted the human race since antiquity-tuberculosis and leprosy in particular. An important contributor to their evolutionary success is their unique cell envelope, which constitutes a quasi-impermeable barrier, protecting the microorganism from external threats, antibiotics included. The arabinofuranosyltransferases are a family of enzymes, unique to the Actinobacteria family that mycobacteria genus belongs to, that are critical to building of this cell envelope. In this chapter, we will analyze available structures of members of the mycobacterial arabinofuranosyltransferase, clarify their function, as well as explore the common themes present amongst this family of enzymes, as revealed by recent research.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Mycobacterium
/
Mycobacterium tuberculosis
Límite:
Humans
Idioma:
En
Revista:
Subcell Biochem
Año:
2022
Tipo del documento:
Article
País de afiliación:
Singapur