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[Related factors of internal border-zone infarcts in patients with symptomatic chronic internal carotid artery occlusion].
Zhai, G J; Xu, Y; Yang, X Y; Sheng, X H; Xiao, G D; Cao, Y J.
Afiliación
  • Zhai GJ; Department of Neurology, the Ninth People's Hospital of Suzhou, Suzhou 215200, China.
  • Xu Y; Department of Neurology, the Ninth People's Hospital of Suzhou, Suzhou 215200, China.
  • Yang XY; Department of Neurology, the Ninth People's Hospital of Suzhou, Suzhou 215200, China.
  • Sheng XH; Department of Neurology, the Ninth People's Hospital of Suzhou, Suzhou 215200, China.
  • Xiao GD; Department of Neurology, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
  • Cao YJ; Department of Neurology, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Zhonghua Yi Xue Za Zhi ; 102(37): 2950-2955, 2022 Oct 11.
Article en Zh | MEDLINE | ID: mdl-36207871
Objective: To explore the related factors of internal border-zone (IBZ) infarcts in patients with symptomatic chronic internal carotid artery occlusion (CICAO). Methods: From January 2011 to May 2019, the symptomatic CICAO patients in the Second Affiliated Hospital of Soochow University and the Ninth People's Hospital of Suzhou were retrospectively analyzed. The patients were divided into IBZ group and non-IBZ group. The demographic data, laboratory examination and imaging data of the two groups were collected. Binary logistic regression analysis was used to identify the related factors of IBZ infarcts in patients with symptomatic CICAO. Results: A total of 185 patients (147 males and 38 females) were finally enrolled, with a mean age of (65±11) years old. There were 64 and 121 cases in IBZ group and non-IBZ group, respectively. The ratio of patients with ophthalmic artery (OA) reflux in IBZ group was 64.1% (41/64), which was significantly higher than that in non IBZ group [47.8% (55/121), P=0.037], while the ratio of patients with collateral compensation (ASTIN/SIR 3-4) in non-IBZ group was 66.1% (80/121), which was significantly higher than that in IBZ group [29.7% (19/64), P<0.001]. Multivariate logistic regression analysis showed that history of cerebral infarction (OR=2.233, 95%CI: 1.023-4.874), low density lipoprotein (LDL) (OR=1.516, 95%CI: 1.006-2.285) and OA reflux (OR=5.060, 95%CI: 1.160-22.081) were independent risk factors for IBZ infarcts in patients with symptomatic CICAO (all P<0.05); while prothrombin international normalized ratio (INR) (OR=0.010, 95%CI: 0.000-0.970) and collateral compensation (ASTIN/SIR 3-4) (OR=0.172, 95%CI: 0.079-0.373) were protective factors (all P<0.05). Conclusion: OA reflux, LDL, and history of cerebral infarction are independent risk factors for IBZ infarcts in patients with symptomatic CICAO, while INR and collateral compensation scores (ASTIN/SIR 3-4) are the protective factors.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arteriopatías Oclusivas / Enfermedades de las Arterias Carótidas Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: Zh Revista: Zhonghua Yi Xue Za Zhi Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arteriopatías Oclusivas / Enfermedades de las Arterias Carótidas Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: Zh Revista: Zhonghua Yi Xue Za Zhi Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: China