Neutrophil to lymphocyte ratio and in-hospital mortality among patients with SARS-CoV-2: A retrospective study.
Ann Med Surg (Lond)
; 82: 104748, 2022 Oct.
Article
en En
| MEDLINE
| ID: mdl-36212733
ABSTRACT
The goal of this study was to investigate in-hospital mortality in patients suffering from acute respiratory syndrome coronavirus 2 (SARS-CoV-2) relative to the neutrophil to lymphocyte ratio (NLR) and to determine if there are gender disparities in outcome. Between February 26 and September 8, 2020, patients having SARS-CoV-2 infection were enrolled in this retrospective cohort research, which was categorized by NLR levels ≥9 and < 9. In total, 6893 patients were involved included of whom6591 had NLR <9, and 302 had NLR ≥9. The age of most of the patients in the NLR<9 group was 50 years, on the other hand, the age of most of the NLR ≥9 group patients was between 50 and 70 years. The majority of patients in both groups were male 2211 (66.1%). The ICU admission time and mortality rate for the patients with NLR ≥9 was significantly higher compared to patients with NLR <9. Logistic regression's outcome indicated that NLR ≥9 (odds ratio (OR), 24.9; 95% confidence interval (CI) 15.5-40.0; p < 0.001), male sex (OR, 3.5; 95% CI 2.0-5.9; p < 0.001) and haemoglobin (HB) (OR, 0.95; 95% CI; 0.94-0.96; p < 0.001) predicted in-hospital mortality significantly. Additionally, Cox proportional hazards analysis (B = 4.04, SE = 0.18, HR = 56.89, p < 0.001) and Kaplan-Meier survival probability plots also indicated that NLR>9 had a significant effect on mortality. NLR ≥9 is an independent predictor of mortality(in-hospital) among SARS-CoV-2 patients.
AÐR, аdjusted Odds Rаtiо; COVID-19; ICU, Intensive Care Unit; In-hospital mortality; NLR; NLR, Neutrophil to lymphocyte ratio; RTPCR, Reverse Transcription Polymerase Chain Reaction; SARS-CoV-2; SÐRS-СоV-2, severe аÑute resÑirаtоry syndrоme Ñоrоnаvirus 2; СI, CоnfidenÑe Intervаl; СRF, Cаse ReÑоrd Fоrm
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Observational_studies
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Prognostic_studies
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Risk_factors_studies
Idioma:
En
Revista:
Ann Med Surg (Lond)
Año:
2022
Tipo del documento:
Article
País de afiliación:
Kuwait