Dendrimer-siRNA Conjugates for Targeted Intracellular Delivery in Glioblastoma Animal Models.

Liyanage, Wathsala; Wu, Tony; Kannan, Sujatha; Kannan, Rangaramanujam M

Liyanage, Wathsala; Wu, Tony; Kannan, Sujatha; Kannan, Rangaramanujam M.

Afiliación

Liyanage W; Center for Nanomedicine, Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States.
Wu T; Center for Nanomedicine, Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States.
Kannan S; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland 21218, United States.
Kannan RM; Center for Nanomedicine, Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States.

ACS Appl Mater Interfaces ; 14(41): 46290-46303, 2022 Oct 19.

Article en En | MEDLINE | ID: mdl-36214413

Asunto(s)

Dendrímeros; Glioblastoma; Ratones; Animales; Glioblastoma/tratamiento farmacológico; ARN Interferente Pequeño/farmacología; Dendrímeros/farmacología; ARN Bicatenario; Modelos Animales; Glutatión; Endonucleasas

Palabras clave

CNS disorders; covalent conjugation; glioblastoma; hydroxyl-terminated PAMAM dendrimer; siRNA; targeted delivery

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Glioblastoma / Dendrímeros Límite: Animals Idioma: En Revista: ACS Appl Mater Interfaces Asunto de la revista: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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