A Method for Assessing Stability of Regional Blood Circulation in Humans.

ABSTRACT

A new non-invasive method for assessing stability of functioning of the human regional circulatory system was developed. The method includes synchronous measurements of the level of cutaneous blood microcirculation of symmetrical areas of paired human organs by laser Doppler flowmetry and subsequent mathematical analysis of Dopplerograms using an original computational and experimental technique based on a mathematical model developed by us in the form of a system of differential equations describing experimental patterns of left-right asymmetry of oscillatory processes in the human regional circulatory system. The proposed method allows evaluating the reserve capabilities of the regional circulatory system in a patient and increases informative value of studies. This non-invasive method can be used in clinical practice to perform a personalized assessment of the stability of regional blood circulation and predict the risks of vascular pathologies.