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Proton pump inhibitor-induced risk of chronic kidney disease is associated with increase of indoxyl sulfate synthesis via inhibition of CYP2E1 protein degradation.
Lu, Shuanghui; Zhao, Jieping; Chen, Xiu; Xu, Shuyu; Yang, Xi; Zhang, Yingqiong; Ma, Zhiyuan; Jiang, Huidi; Zhou, Hui.
Afiliación
  • Lu S; Institute of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
  • Zhao J; Institute of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
  • Chen X; Institute of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
  • Xu S; Institute of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.
  • Yang X; College of Medicine, Zhejiang University, Hangzhou, China.
  • Zhang Y; Institute of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China; College of Medicine, Zhejiang University, Hangzhou, China.
  • Ma Z; College of Medicine, Zhejiang University, Hangzhou, China.
  • Jiang H; Institute of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China; Hangzhou Institute of Innovative Medicine, Zhejiang University, Hangzhou, China. Electronic address: hdji
  • Zhou H; Institute of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China. Electronic address: zhouhui@zju.edu.cn.
Chem Biol Interact ; 368: 110219, 2022 Dec 01.
Article en En | MEDLINE | ID: mdl-36243147
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Renal Crónica / Inhibidores de la Bomba de Protones Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Chem Biol Interact Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Irlanda
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Renal Crónica / Inhibidores de la Bomba de Protones Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Chem Biol Interact Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Irlanda